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DoD funds development of anthrax vaccine patch

first_imgApr 8, 2008 (CIDRAP News) – Iomai Corp., a biotechnology company that specializes in needle-free vaccines, announced today that it will receive a grant from the US Department of Defense (DoD) to fund preclinical development of a patch-based anthrax vaccine.The 1-year grant to Iomai, based in Gaithersburg, Md., will be in the form of a $943,856 cost reimbursement from the US Army Medical Research and Material Command, according to a press release from Iomai.Work on the vaccine will combine an antigen developed by Avecia Biologics, Ltd., based in the United Kingdom, with an Iomai adjuvant on a skin patch. Iomai said its next step would be to gauge the stability of the patch to see if it can be stored and shipped at room temperature.The current licensed anthrax vaccine, made by Emergent BioSolutions Inc., must be refrigerated and is given as a six-shot regimen over 18 months. The US government has been seeking a second-generation product to replace anthrax vaccine adsorbed (AVA), developed in the 1950s, with hopes that a newer product would require fewer doses and produce minimal side effects. Some military personnel have objected to AVA because of reported serious side effects.”The military has a clear need for an effective anthrax vaccine that can be stockpiled and shipped at room temperature, and we believe that Iomai has the scientific know-how and the manufacturing ability to meet that need,” said Stanley C. Erck, Iomai’s president and chief executive officer, in the press release.Iomai says it has developed techniques for drying proteins, such as the anthrax vaccine, to allow administration with a patch the size of an adhesive bandage. The company says it has four other products using the protein-drying technology in its development pipeline; three are aimed at seasonal and pandemic influenza and the other at travelers’ diarrhea.On Apr 2, PharmAthene, an Annapolis, Md., biodefense company, announced that it had finalized its acquisition of the biodefense vaccine business of Avecia, Iomai’s anthrax vaccine partner. Iomai acknowledged the sale in its press release but did not give any details about how it would affect preclinical work on the anthrax vaccine patch.PharmAthene, in its press release, said it had acquired all of the assets related to Avecia’s vaccines business, including intellectual property rights to its recombinant protective antigen (rPA) anthrax vaccine and plague vaccine, as well as government contracts relating to the vaccines that total $60 million.Avecia has completed phase 2 clinical studies of its rPA anthrax vaccine, according to PharmAthene. In February, the US Department of Health and Human Services (HHS) issued a request for proposals for an anthrax rPA vaccine for the Strategic National Stockpile (SNS), the company said in its press release. The HHS proposal request calls for a company to produce 25 million doses of anthrax vaccine.On Mar 24, the Wall Street Journal reported that the government’s anthrax vaccine contract could be worth more than $400 million.David P. Wright, PharmAthene’s president and chief executive officer, said in the press release that preclinical and clinical studies of Avecia’s anthrax vaccine show an antibody response and that it is safe and well tolerated.”If these results are confirmed in future studies, we believe this vaccine could prove to be a superior choice for procurement in the Strategic National Stockpile for civilian defense against anthrax threats,” he said.Federal officials have hit roadblocks in their efforts to add a second-generation anthrax vaccine to the national stockpile. In December 2006, HHS canceled an $877 million contract with VaxGen, a small biotechnology company based in Brisbane, Calif., after the company had problems with its vaccine’s stability and missed a deadline for starting a clinical trial.In October 2007, a report from the Government Accountability Office (GAO) criticized federal anthrax vaccine procurement efforts, saying officials awarded the contract prematurely, had unrealistic expectations of VaxGen, and were confused about how the vaccine would be used.See also:Apr 8 Iomai press releaseApr 2 PharmAthene press release Oct 31, 2007, CIDRAP News story “GAO critiques anthrax vaccine procurement, management”last_img read more

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Indian Super League 2019-20 Live Streaming: When and Where to Watch ATK vs Jamshedpur FC Telecast

first_img Get the best of News18 delivered to your inbox – subscribe to News18 Daybreak. Follow News18.com on Twitter, Instagram, Facebook, Telegram, TikTok and on YouTube, and stay in the know with what’s happening in the world around you – in real time. ATK will host Jamshedpur FC on November 9, Saturday, for the Indian Super League 2019-20 match number 19. The ISL 2019-20 ATK vs Jamshedpur FC will be played at the Vivekananda Yuba Bharati Krirangan in Kolkata. ATK will eye successive wins when they take on the Jamshedpur side at their home turf. Meanwhile, an unbeaten Jamshedpur FC, who held the defending champions Bengaluru FC to a draw in their last game, will be eyeing a victory in this Top 4 clash. The Indian Super League 2019-20 ATK vs Jamshedpur FC will commence at 7:30PM.Speaking on Jamshedpur’s positive start, head coach Antonio Iriondo said, “I am happy with seven points. At the beginning of the league, it’s a very good thing. Especially when you consider that we are a new team and we are trying to adjust. I think it’s a very good situation to have seven points at this moment. We will keep improving and we will have the team that we want.” Meanwhile, ATK head coach Antonio Lopez Habas praised his side for keeping a clean sheet against Chennaiyin FC. “I think in the first-half, Chennaiyin had a few chances and we were also denied by a wrong offside call. But in the second-half, I thought my defence was tighter. We made some individual errors but that’s the result of not attacking more in the second-half. But the defence was good, solid and positive. You can play well sometimes and not win but we won, which is why I think it was a good match for us,” he said.Indian Super League 2019-20 ATK Probable Line-up vs Jamshedpur FC: Arindam Bhattacharja (GK), Pritam Kotal, Carl McHugh, Agustin Iniguez, Prabir Das; Pronay Halder, Jayesh Rane, Edu Garcia; Michael Soosairaj, David Williams, Roy Krishna.Indian Super League 2019-20 Jamshedpur FC Probable Line-up vs ATK: Subrata Paul (GK), Tiri, Joyner Lourenco, Keegan Pereira, Robin Gurung; Noe Acosta, Piti, Memo Moura; Farukh Choudhary, Aniket Jadhav, Sergio Castel.This year a total of 10 teams are participating in the tournament. These teams are Odisha FC, Kerala Blasters FC, Bengaluru FC, ATK, NorthEast United FC, Hyderabad FC, Mumbai City FC, Chennaiyin FC, FC Goa and Jamshedpur FC.What time will Indian Super League 2019-20 ATK vs Jamshedpur FC match start?ISL 2019-20 ATK vs Jamshedpur FC match will start at 7:30PM on Saturday, November 9. The ATK vs Jamshedpur FC fixture will be at the Vivekananda Yuba Bharati Krirangan in Kolkata.Where to watch Indian Super League 2019-20 ATK vs Jamshedpur FC match on TV?The ATK vs Jamshedpur FC match can be viewed on the television sets on sports channel Star Sports 2 and Star Sports 2 HD.Where to watch Indian Super League 2019-20 ATK vs Jamshedpur FC on live streaming?The live streaming of ATK vs Jamshedpur FC match, Indian Super league 2019-20 will be available on Hotstar and Jio TV. atkfootballindian footballindian super league First Published: November 9, 2019, 2:46 PM ISTlast_img read more

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